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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEATR1
All Species:
15.15
Human Site:
T721
Identified Species:
25.64
UniProt:
Q9H583
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H583
NP_060542.4
2144
242370
T721
C
C
S
S
L
K
E
T
H
F
P
F
A
I
R
Chimpanzee
Pan troglodytes
XP_001156974
2144
242420
T721
C
C
S
S
L
K
E
T
H
F
P
F
A
I
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536334
2141
242568
A721
C
C
S
S
L
K
E
A
H
F
P
F
A
I
R
Cat
Felis silvestris
Mouse
Mus musculus
NP_659084
2143
242053
T721
C
C
S
S
F
Q
E
T
C
F
P
F
A
L
R
Rat
Rattus norvegicus
NP_001101888
2143
241191
T721
C
C
S
S
L
R
E
T
C
F
P
F
A
I
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422958
2155
244590
K721
C
C
C
N
L
Q
M
K
E
K
Y
F
S
V
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7SY48
2159
242032
S717
S
L
Q
S
M
T
E
S
Q
H
L
H
T
A
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VM75
2096
237201
L717
T
A
Y
A
K
R
E
L
Q
P
R
E
S
L
H
Honey Bee
Apis mellifera
XP_393800
2028
231830
V683
Q
P
E
V
A
R
E
V
I
E
M
A
T
E
M
Nematode Worm
Caenorhab. elegans
Q23495
1650
185210
E367
L
S
K
D
A
E
S
E
D
N
T
L
A
I
D
Sea Urchin
Strong. purpuratus
XP_794611
1635
181917
A352
N
I
T
P
L
L
A
A
L
L
P
H
L
T
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C8Z4
2001
224001
S682
R
A
C
N
Y
K
L
S
E
V
L
E
T
C
S
Baker's Yeast
Sacchar. cerevisiae
P42945
1769
200063
E486
T
N
V
S
M
L
T
E
T
G
E
R
Y
K
K
Red Bread Mold
Neurospora crassa
Q7RZM8
1788
196873
A505
P
Q
T
A
S
C
F
A
E
E
P
L
D
L
L
Conservation
Percent
Protein Identity:
100
99.5
N.A.
89.7
N.A.
83.8
84.9
N.A.
N.A.
65.5
N.A.
54.5
N.A.
28.6
30.5
21.1
24.4
Protein Similarity:
100
99.8
N.A.
95
N.A.
92.1
92.7
N.A.
N.A.
80.5
N.A.
73
N.A.
49.4
50.8
38.9
43.2
P-Site Identity:
100
100
N.A.
93.3
N.A.
73.3
80
N.A.
N.A.
26.6
N.A.
13.3
N.A.
6.6
6.6
13.3
13.3
P-Site Similarity:
100
100
N.A.
93.3
N.A.
86.6
93.3
N.A.
N.A.
53.3
N.A.
33.3
N.A.
33.3
13.3
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.4
21.2
23
Protein Similarity:
N.A.
N.A.
N.A.
43.4
40.2
42.2
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
0
15
15
0
8
22
0
0
0
8
43
8
8
% A
% Cys:
43
43
15
0
0
8
0
0
15
0
0
0
0
8
0
% C
% Asp:
0
0
0
8
0
0
0
0
8
0
0
0
8
0
8
% D
% Glu:
0
0
8
0
0
8
58
15
22
15
8
15
0
8
0
% E
% Phe:
0
0
0
0
8
0
8
0
0
36
0
43
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
22
8
0
15
0
0
8
% H
% Ile:
0
8
0
0
0
0
0
0
8
0
0
0
0
36
0
% I
% Lys:
0
0
8
0
8
29
0
8
0
8
0
0
0
8
15
% K
% Leu:
8
8
0
0
43
15
8
8
8
8
15
15
8
22
8
% L
% Met:
0
0
0
0
15
0
8
0
0
0
8
0
0
0
8
% M
% Asn:
8
8
0
15
0
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
8
8
0
8
0
0
0
0
0
8
50
0
0
0
0
% P
% Gln:
8
8
8
0
0
15
0
0
15
0
0
0
0
0
8
% Q
% Arg:
8
0
0
0
0
22
0
0
0
0
8
8
0
0
29
% R
% Ser:
8
8
36
50
8
0
8
15
0
0
0
0
15
0
8
% S
% Thr:
15
0
15
0
0
8
8
29
8
0
8
0
22
8
8
% T
% Val:
0
0
8
8
0
0
0
8
0
8
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
8
0
0
0
0
0
8
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _